Better identify, diagnose and treat rare cancer patients
The Alcimed team has been exploring for more than 25 years the field of rare cancers such as for example sarcoma or different types of carcinoma. We support our clients to better understand where patients are located, how research can bring benefits and how new types of treatments can be established at valued costs and return on investment.
THE CHALLENGES RELATED TO RARE CANCERS AND RARE TUMORS
What is the definition of a rare cancer?
Rare cancers or rare tumors are a group of cancers that collectively account for a small percentage of all cancer cases, although this “small” number accounts for up to 25% of all new cancer cases. A rare cancer is defined as a cancer that affects fewer than 6 out of 100,000 people per year. This definition based on incidence is rather new and aims at better focusing the light and the efforts on the less frequent cancers. So rare cancers are rare diseases in majority, even if a rare disease is defined by prevalence.
However, the definition of a rare cancer can be expanded towards patient populations that have no treatment options anymore, or patients that receive very personalized treatment types as their number can be very small.
There are many different types of rare cancers, each with its own unique characteristics and treatment challenges. Examples of rare cancers include mesothelioma, sarcomas, pancreatic neuroendocrine tumors, and some types of pediatric cancers.
What are the challenges related to rare cancers?
Because a rare tumor is relatively not common, there is often limited research and treatment options available for these diseases. People with rare tumors may face difficulties in obtaining a timely and accurate diagnosis, as well as in finding appropriate treatment options. Likewise, the level of information and awareness is relatively small and aggravates the health issues for patients as many physicians cannot connect the dots and won’t recognize unspecific symptoms with a rare cancer.
A rare cancer also can have a significant psychosocial impact on patients and their families, as they may feel isolated and unsupported due to the lack of awareness and knowledge about the disease.
They also represent a difficult field for pharma players. Indeed, research can be difficult as not many patients are available. Likewise, and for the same reason, clinical trial development can be lengthy and costly and reimbursement outcome is often unclear in case payers are not convinced in the safety or efficacy of a new drug.
How can we increase awareness and who are the best targets? How to optimize diagnostic procedures and health pathways?
How can we help lower costs in rare tumor developments? What is the state-of-the-art around biomarkers for rare cancers?
How can we plan and execute clinical trials to avoid regulatory issues as well as to gain high reimbursement rates? In which cases a new treatment for a type of rare cancer can benefit from orphan designation?
HOW DO WE SUPPORT YOU IN YOUR RARE CANCERS PROJECTS?
For more than 25 years, Alcimed has been supporting its clients on many issues related to rare diseases on one side, and in oncology on the other side. As rare cancers are naturally at the crossroads between the two, we have developed a great experience in this field, through our projects and our continuous monitoring of this field. Do not hesitate to visit our Oncology Resource Center to find out more!
The diversity of our clients (pharmas, biotechs, research centers, professional associations, national institutions, …), the geographical fields we explore, and the types of projects we carry out, gives us a global and in-depth understanding of the issues addressed in the field of rare cancers.
Our projects include topics as diverse as new technologies and therapeutic approaches for orphan diseases, understanding disease management and patient care pathways, assessment of market opportunities and licensing, market access, pricing and reimbursement, regulatory evolution, and operational support (patient identification, optimization of care pathways, etc.).
EXAMPLES OF RECENT PROJECTS CARRIED OUT FOR OUR CLIENTS IN RARE CANCERS
Our purpose? Helping both private and public decision-makers explore and develop their uncharted territories: new technologies, new offers, new geographies, possible futures, and new ways to innovate.
Located across eight offices around the world (France, Europe, Singapore and the United States), our team is made up of 220 highly-qualified, multicultural and passionate explorers, with a blended science/technology and business culture.
Our dream? To build a team of 1,000 explorers, to design tomorrow's world hand in hand with our clients.
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