Translational research

Translational research Agency Consulting firm Experts Specialists Consultancy

Boost your therapeutic innovation

Alcimed’s Healthcare team supports healthcare companies in capturing the potential of translational research in order to accelerate the development of their innovative therapeutic projects.

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    The challenges related to translational research

    Translational research has seen rapid growth in recent years thanks to the boom of cutting-edge technologies and increasing collaboration between scientists and health professionals.

    Among these modern technologies, medical advances in DNA sequencing and data analysis have driven key advances in understanding the molecular mechanisms of disease and identifying new therapeutic targets. Today, precision medicine has emerged as a promising method for personalizing treatments based on individual patient characteristics, and therefore relies heavily on translational research.

    The importance of translational research is highlighted by the recent increases in investments in this domain: public and private players including the National Institute of Health (NIH), European Medicines Agency (EMA), the National Institute for Health Research (NIHR), and others have invested large sums and encouraged collaborations between researchers, clinicians, and companies.

    In order for this market to develop, numerous challenges exist for the involved players. Some of the more notably challenges include the following:

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      How we support you in your projects related to translational research 

      For over 30 years, Alcimed has been supporting clients in the healthcare domain in numerous issues, including those pertaining to translational research.

      We have carried out projects in this domain with all types of healthcare players, and notably:

      • European Centers of National Research including Precidiab, l’INCa, and others
      • Medtech companies including bioMérieux, Medtronic, and others
      • Patients associations such as the French Society for Analytical Psychology (SFPA)
        The diversity of our clients, the geographies we explore, and the types of projects we carry out give us a global and in-depth understanding of the issues faced in healthcare R&D, and more specifically, in translational research.

      Our projects cover diverse subjects such as new technologies and therapeutic approaches, the identification and prioritization of potential partners in translational research, the definition of collaborative projects, building grant funding applications, preparing to launch new projects in translational medicine, and many others!

      Examples of recent projects carried out for our clients in translational research

      • Strategic positioning and help in creating a translational research center

        Alcimed supported a public biomedical research institute to specify their interest in creating a translational research center or not, and if interested, to define their strategic position.

        The frame of the translational research covered all research steps upstream of medication (discovery phase), from fundamental research to creation of an optimized medication candidate (lead). Our team supported the client in the studies of the current situation of their translational research programs and the identification of unaddressed needs, and analyzed the areas in which a specific structure would fill the gaps.

        After the project, the client had the necessary information to decide whether to establish a translational research laboratory for developing medications.

      • Search and evaluation of translational research partners for new technologies

        We supported a leader in the in-vitro diagnostic (IVD) field for whom innovation is a key development pillar. Our client wanted to enrich their external partner network in order to better identify, evaluate and develop the future technologies in the IVD field. These technologies are linked to a broad field of analytical scientific expertise, such as lasers, mass spectrometry, nuclear resonance magnetic spectroscopy, and also preparation and automation of test tubes and data studies.

        As a first step, Alcimed identified potential expert partners in this domain (both public and private players) that had the capacity for translational research and that would be open for collaboration. These players were then characterized and prioritized by our team based on different criteria in order to select the best potential partners.

        This study allowed our client to obtain a view of all of the different potential partners, a recommendation for which partners to target first, and the key associated contacts to initiate first collaborations.

      • R&D and translational research strategies for a pharmaceutical laboratory

        Our client, a leading pharmaceutical laboratory in the ophthalmology market, was lacking in reasons to decide whether or not to develop a translational research programs in its R&D strategy. We helped them in exploring the primary barriers and the associated levers to put in place in translational research, focusing mainly on benchmark cases. Our studies focused on three main points:

        1. Identifying good practices for a pharmaceutical company to implement translational research activities
        2. Determining the potential of applying translational research in the ophthalmology field
        3. Defining the optimal organization of our client’s resources

        In the end, our study enabled the client to have a complete vision on the ins and outs of translational research programs and the potential implications that their implementation could have on their global R&D strategy.

      • Search for public and semi-public funding opportunities for the creation of a translational R&D center for mRNA

        A leading pharmaceutical client had launched a medical center of excellence in mRNA in 2021 that was dedicated to vaccines, with the objective of accelerating the development and delivery of next-generation vaccines.

        Our client wanted to maintain this dynamic by opening a medical center of development for mRNA technologies dedicated to preclinical, clinical, and translational research activities. Our team initially identified public and semi-public financing opportunities for this project, then characterized them (concerned domains, eligibility criteria, funding amount, etc.) and selected the best opportunities by taking into account the needs and specific context of the client.

        Finally, Alcimed equally supported the client in developing their roadmap in this new R&D center.

      • Identification for a leading pharmaceutical company of the key capabilities needed for industrializing its ASO technology

        Alcimed helped a leading pharmaceutical R&D company identify the critical capabilities required for the successful industrialization of molecules using antisense oligonucleotide (ASO) technology.

        To do so, we analyzed the competitive landscape and trends, identified the skills and capabilities needed to penetrate this market, and the implications for the various teams, particularly in terms of translational research and associated partners.

        Thanks to our work, our client was able to understand the current competitive position of ASO technology, and to anticipate the critical capabilities and competencies needed to successfully industrialize ASO as well as future partners in translational medicine.

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